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[Remote] Senior Software Engineer II

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. Freenome is seeking a Senior Software Engineer to join their Platform team, which focuses on enabling scientific innovation and data intelligence for multi-cancer detection blood tests. The role involves leading projects, collaborating with cross-functional teams, and enhancing the platform architecture to support R&D and business analytics.

Responsibilities

  • Lead projects end to end and contribute to impactful platform initiatives that power R&D, operational excellence and business intelligence analytics
  • Partner with engineers, scientists, product managers and business teams to identify high-leverage opportunities and build common solutions
  • Integrate open-source, enterprise and SaaS technologies into our evolving stack
  • Design and ship components of a new platform architecture to enable multi-tenancy, fine-grained data governance, workload isolation and scaling
  • Contribute to the growth of our Data Lakehouse platforms, enabling well governed data products for analytical and operational use cases
  • Continuously improve the Research Platform to meet our Science’s evolving needs for experimentation, ML Ops, data processing and analysis
  • Help shape how we approach data modeling, context engineering and emerging semantic layers to make data easier to discover and to use
  • Advocate for a product mindset within Platform and Data engineering at Freenome, focusing on developer effectiveness and platform usability
  • Explore and pilot AI-assisted or agentic workflows to enhance individual and team productivity, sharing learnings with the broader organization
  • Collaborate through system design, code reviews and pairing, promoting a strong team culture of accountability, learning, and psychological safety
  • Support platform users to troubleshoot issues and unblock critical work
  • Model Freenome’s values and principles in your work and interactions

Skills

  • 6+ years of experience building and operating highly reliable production software systems, preferably in platform engineering teams or similar
  • Proficiency with Python and experience with one or more other high-level programming languages
  • Strong knowledge of Linux fundamentals including networking and containerization
  • Hands-on experience operating cloud services, storage and compute using IaC with at least one major cloud provider, preferably Azure or GCP
  • Operational experience managing and optimizing large Kubernetes clusters, preferably in single or multi-cluster environments with thousands of nodes
  • A pragmatic approach to reliability, observability, performance tuning, and operational excellence
  • Excellent communication and documentation skills
  • Comfort with cross-functional collaboration and navigating tradeoffs
  • BS or higher in computer science or a related technical field, or comparable experience
  • Columnar data processing, open lakehouse technologies and table formats
  • Supporting researchers, data scientists, AI/ML teams
  • Flyte or other modern workflow orchestrators
  • Everything as Code approach to infrastructure, policies, data
  • Operating production systems in Microsoft Azure
  • Open-Source contribution and maintenance

Benefits

  • Equity
  • Cash bonuses
  • A full range of medical, financial, and other benefits depending on the position offered

Company Overview

  • Freenome is a biotechnology company developing blood tests for early cancer detection to improve access to routine screening. It was founded in 2014, and is headquartered in South San Francisco, California, USA, with a workforce of 201-500 employees. Its website is https://www.freenome.com.
  • Company H1B Sponsorship

  • Freenome has a track record of offering H1B sponsorships, with 7 in 2025, 11 in 2024, 15 in 2023, 10 in 2022, 7 in 2021, 7 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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